Predominant immunoglobulin in follicular fluid is?

VGO-0230

QUESTION

Predominant immunoglobulin in follicular fluid is?

OPTIONS

(A) IgM
(B) IgG
(C) IgA
(D) IgE

ANSWER

(B) IgG

EXPLANATION

IgG is generally the predominant immunoglobulin in follicular fluid, reflecting its abundance in blood and passage into the follicular compartment. IgM is a larger pentamer with more restricted passage, IgA is especially important in mucosal secretions, and IgE occurs at much lower concentrations and is associated with hypersensitivity and antiparasitic responses. These differences favor IgG as the principal class in this fluid.

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