The calf affected with Klinefelter syndrome possesses which of the gene pairs?

VGO-0045

QUESTION

The calf affected with Klinefelter syndrome possesses which of the gene pairs?

OPTIONS

(A) XXY
(B) XYY
(C) XXX
(D) None of the above

ANSWER

(A) XXY

EXPLANATION

Klinefelter syndrome is associated with an additional X chromosome in an otherwise male sex-chromosome complement, conventionally represented as XXY. This can impair testicular development and fertility. XYY represents a different sex-chromosome aneuploidy, and XXX describes an additional X chromosome in a female complement. Since XXY is specifically listed, none of the above is inappropriate.

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