VGO-0187
QUESTION
For synchronization of oestrus which of the following hormone has disadvantage because of its long half-life?
OPTIONS
(A) Oestrogen
(B) FSH
(C) PGF2α
(D) PMSG
ANSWER
(D) PMSG
EXPLANATION
PMSG, now termed eCG, has a prolonged circulating half-life because of its glycoprotein structure and extensive sialylation. Persistent stimulation can produce prolonged follicular activity and reduce precise control of a synchronization or superovulation response. FSH is cleared more rapidly, and estrogen and PGF2alpha do not have this characteristic prolonged gonadotropic action. PMSG therefore has the stated disadvantage.
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Veterinary Gynaecology and Obstetrics · 240 Questions
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