Theca cells are stimulated by?

VGO-0109

QUESTION

Theca cells are stimulated by?

OPTIONS

(A) LH
(B) FSH
(C) Prolactin
(D) Estradiol

ANSWER

(A) LH

EXPLANATION

LH stimulates ovarian theca interna cells to synthesize androgens. These androgens pass to granulosa cells, where FSH-supported aromatase converts them to estrogens. Prolactin is not the principal gonadotropin acting on theca cells, and estradiol is a steroid product and regulator rather than the primary stimulating pituitary hormone. This relationship is the basis of the two-cell, two-gonadotropin model.

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