The natural luteolysing agent is?

VGO-0199

QUESTION

The natural luteolysing agent is?

OPTIONS

(A) Progesterone
(B) Estrogen
(C) PGF2 alpha
(D) None of the above

ANSWER

(C) PGF2 alpha

EXPLANATION

Prostaglandin F2alpha is the principal physiological luteolytic agent in many domestic species, causing regression of a responsive corpus luteum and a fall in progesterone secretion. Progesterone supports the luteal reproductive environment rather than directly acting as the normal luteolysin. Estrogen can regulate luteolytic pathways in a species-dependent manner but is not the direct natural agent intended here.

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