The primordial germ cells arise?

VGO-0171

QUESTION

The primordial germ cells arise?

OPTIONS

(A) Intragonadally
(B) Extragonadally
(C) At the time of birth
(D) At the time of puberty

ANSWER

(B) Extragonadally

EXPLANATION

Primordial germ cells are initially identifiable outside the developing gonad and subsequently migrate to the genital ridges. Their extragonadal origin and migration distinguish them from local gonadal somatic cells. They do not first arise at birth or puberty, because germ-cell development begins during embryonic life. Intragonadal is therefore not the correct description of their initial developmental location.

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