VPT-0142
QUESTION
Transport across the GI mucosal barrier is effective when?
OPTIONS
(A) The drug is dissolved in GIT lumen
(B) The drug is stable chemically or enzymatically
(C) The drug is lipid soluble and not completely ionized
(D) All of the above
ANSWER
(D) All of the above
EXPLANATION
Effective gastrointestinal absorption requires the drug to be dissolved, chemically and enzymatically stable enough to survive the lumen, and sufficiently lipid soluble and nonionized to cross mucosa. Therefore all of the above is correct.
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Veterinary Pharmacology and Toxicology · 167 Questions
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