VPT-0081
QUESTION
The persistent cough associated with ACE inhibitor therapy is due to?
OPTIONS
(A) Prostaglandins
(B) Leukotrines
(C) Kinnins
(D) Rennin
ANSWER
(C) Kinnins
EXPLANATION
ACE inhibition reduces bradykinin breakdown, so accumulated kinins contribute to the persistent dry cough associated with ACE inhibitors. Prostaglandins, leukotrienes, and renin are not the principal mediator responsible for this characteristic adverse effect.
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Veterinary Pharmacology and Toxicology · 167 Questions
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