Large molecular size polar compounds are preferentially excreted through?

VPT-0116

QUESTION

Large molecular size polar compounds are preferentially excreted through?

OPTIONS

(A) Renal
(B) Biliary
(C) Pulmonary
(D) All of the above

ANSWER

(B) Biliary

EXPLANATION

Large polar molecules are poorly filtered through the glomerulus and are preferentially eliminated into bile when hepatic transport permits. Renal excretion favors smaller, water-soluble molecules, while pulmonary excretion is mainly relevant to volatile substances and gases.

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