Consider following statements: (a) Compared with mammalian and avian species the half-lives of antimicrobials in fish and reptiles are prolonged. (b) In poikilothermic spices, half-life of antimicrobial related to the lower metabolic turnover rate?

VPT-0062

QUESTION

Consider following statements:
(a) Compared with mammalian and avian species the half-lives of antimicrobials in fish and reptiles are prolonged.
(b) In poikilothermic spices, half-life of antimicrobial related to the lower metabolic turnover rate.

OPTIONS

(A) Both the statements are correct and second is the correct explanation of the first.
(B) Neither of the statements are correct.
(C) Both the statements are correct but second is not the correct explanation for the first.
(D) The first statement is correct, not the second.

ANSWER

(A) Both the statements are correct and second is the correct explanation of the first.

EXPLANATION

Fish and reptiles generally have prolonged antimicrobial half-lives compared with mammals and birds because their poikilothermic physiology is associated with a lower metabolic turnover rate. Both statements are therefore correct, and the second explains the first.

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