VPT-0087
QUESTION
The glucocorticoid-induced protein that targets phospholipase A2 is?
OPTIONS
(A) Calmodulin
(B) Mx protein
(C) Phospholamban
(D) Annexin 1
ANSWER
(D) Annexin 1
EXPLANATION
Annexin 1, also called lipocortin 1, is induced by glucocorticoids and inhibits phospholipase A2, thereby reducing arachidonic-acid release and eicosanoid formation. Calmodulin, Mx protein, and phospholamban do not mediate this glucocorticoid action.
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Veterinary Pharmacology and Toxicology · 167 Questions
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