Bacterial susceptibility to β-lactam antibiotics depends upon?

VPT-0128

QUESTION

Bacterial susceptibility to β-lactam antibiotics depends upon?

OPTIONS

(A) Production of β-lactamases
(B) Permeability of cell wall
(C) Sensitivity of penicillin binding protein
(D) All of the above

ANSWER

(D) All of the above

EXPLANATION

Bacterial response to beta-lactams depends on beta-lactamase production, drug penetration through the cell envelope, and the susceptibility of penicillin-binding proteins. Since all three factors influence susceptibility, all of the above is correct.

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