VMC-0084
QUESTION
The source of complement for CFT?
OPTIONS
(A) Rabbit serum
(B) Chicken serum
(C) Dog serum
(D) Guinea Pig Serum
ANSWER
(D) Guinea Pig Serum
EXPLANATION
Complement used in the classical complement fixation test is traditionally supplied by fresh guinea pig serum because it provides a reliable source of complement with low nonspecific antibody interference. Therefore option D is correct; rabbit, chicken, and dog sera are not the standard complement source for CFT.
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