The specific regions of antigens, against which immune response are directed, are called?

VMC-0073

QUESTION

The specific regions of antigens, against which immune response are directed, are called?

OPTIONS

(A) Idiotopes
(B) Paratopes
(C) Antitopes
(D) Epitopes

ANSWER

(D) Epitopes

EXPLANATION

The specific part of an antigen recognized by an antibody or T-cell receptor is called an epitope, or antigenic determinant. Therefore option D is correct; an idiotope is an antigenic determinant on an antibody variable region, a paratope is the antigen-binding site of an antibody, and 'antitope' is not the standard term.

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