VPP-0069
QUESTION
Most infarct tissues undergo coagulative necrosis except for the following organ, wherein it undergoes liquefaction?
OPTIONS
(A) Kidney
(B) Brain
(C) Liver
(D) Lung
ANSWER
(B) Brain
EXPLANATION
Most infarcts undergo coagulative necrosis because ischemia causes protein denaturation while preserving tissue architecture for a time. The major exception is the brain, where ischemic injury characteristically results in liquefactive necrosis because of enzymatic digestion of nervous tissue. Kidney, liver, and lung infarcts generally show coagulative necrosis. Hence, option B is correct.