VPP-0034
QUESTION
The following test is most sensitive for detection of ketone bodies in urine?
OPTIONS
(A) Benedicts test
(B) Benzidine test
(C) Robert’s test
(D) Rothera’s test
ANSWER
(D) Rothera’s test
EXPLANATION
Rothera's test is a standard qualitative test for ketone bodies in urine and is based on the reaction of ketone bodies with sodium nitroprusside in an alkaline medium to produce a characteristic color reaction. Benedict's test detects reducing sugars, benzidine is associated with occult blood testing, and Robert's test is not the most sensitive test for ketonuria. Therefore, option D is correct.