VPP-0036
QUESTION
Assay of which of the following enzymes is not useful in the diagnosis of myocardial infarction?
OPTIONS
(A) ALT
(B) AST
(C) CPK
(D) LDH
ANSWER
(A) ALT
EXPLANATION
ALT is not a useful primary enzyme marker for myocardial infarction because it is more strongly associated with hepatocellular injury and lacks the cardiac specificity of other enzymes. AST, creatine phosphokinase/creatine kinase, and LDH have historically been used in evaluating myocardial injury, although modern cardiac troponins are more specific. Therefore, option A is correct.