VPP-0009
QUESTION
Most cell damaging free radical is?
OPTIONS
(A) Superoxide
(B) Hydrogen peroxide
(C) Hydroxy radicals
(D) Singlet oxygen
ANSWER
(C) Hydroxy radicals
EXPLANATION
Hydroxyl radicals are among the most reactive and damaging free radicals generated during oxidative stress because they react rapidly with lipids, proteins, carbohydrates, and nucleic acids near their site of formation. Superoxide and hydrogen peroxide are generally less reactive, while singlet oxygen can also cause oxidative injury but is not as broadly destructive as the hydroxyl radical. Therefore, option C is correct.