VPY-0080
QUESTION
Among the following which is not isotonic?
OPTIONS
(A) 0.9% sodium chloride
(B) 5.0% dextrose
(C) 7.5% sodium chloride
(D) 0.45% sodium chloride and 2.5% dextrose
ANSWER
(C) 7.5% sodium chloride
EXPLANATION
7.5% sodium chloride is the correct option because 7.5% NaCl is markedly hypertonic relative to plasma and therefore is not isotonic. 0.9% NaCl is isotonic, 5% dextrose is approximately isotonic in the infusion bag, and 0.45% NaCl with 2.5% dextrose has an approximate osmolarity close to the isotonic range used clinically.
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