VMD-0087
QUESTION
In Crush syndrome, the lesions are found in which portion of nephron?
OPTIONS
(A) Lower portion of tubules
(B) Bowman’s capsule
(C) Upper portion of tubules
(D) Glomeruli
ANSWER
(A) Lower portion of tubules
EXPLANATION
Crush syndrome can cause pigment nephropathy from myoglobin released by damaged muscle, with tubular obstruction and necrosis particularly affecting the distal or lower portions of renal tubules. Bowman’s capsule and glomeruli are not the primary sites of the characteristic crush-related tubular lesion.
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