VPP-0050
QUESTION
Anaplastic cells show nuclear-cytoplasmic ratio of?
OPTIONS
(A) 1 : 1
(B) 1 : 4
(C) 1 : 6
(D) 1 : 12
ANSWER
(A) 1 : 1
EXPLANATION
Anaplastic malignant cells commonly show a high nuclear-to-cytoplasmic ratio, often approaching 1:1 because of enlarged hyperchromatic nuclei and relatively scant cytoplasm. Ratios such as 1:4, 1:6, or 1:12 indicate progressively more cytoplasm and are less characteristic of marked anaplasia. Hence, option A is correct.