VPP-0004
QUESTION
Langhan’s giant cell is observed in?
OPTIONS
(A) Brucellosis
(B) Leptospirosis
(C) Tuberculosis
(D) Listeriosis
ANSWER
(C) Tuberculosis
EXPLANATION
Langhans giant cells are multinucleated macrophages with nuclei arranged characteristically at the periphery and are a classic feature of granulomatous inflammation in tuberculosis. Brucellosis and leptospirosis do not classically produce Langhans giant cells, and listeriosis is more characteristically associated with microabscesses and suppurative inflammation. Therefore, option C is correct.