VSR-0042
QUESTION
Ketamine is used in cats for restraint and exerts its CNS actions mainly inhibiting the?
OPTIONS
(A) M1 receptor operated channels
(B) GABA receptor operated channels
(C) NMDA receptor operated channels
(D) None of the above
ANSWER
(C) NMDA receptor operated channels
EXPLANATION
Ketamine's principal dissociative effect results from antagonism of NMDA receptor-operated ion channels. Muscarinic receptors and GABA-operated channels are targets for different drug actions, so 'none' is excluded by the NMDA mechanism.
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Veterinary Surgery and Radiology · 200 Questions
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