AGB-0033
QUESTION
Peptide growth factor that increases the success of establishing and maintain ES cell lines?
OPTIONS
(A) ESF
(B) FSH
(C) PGF2
(D) LIF
ANSWER
(D) LIF
EXPLANATION
Leukemia inhibitory factor (LIF) is a cytokine that supports the maintenance of pluripotency and self-renewal of many mouse embryonic stem cell lines in culture. FSH regulates gonadal function, PGF2α has reproductive/luteolytic functions, and ESF is not the standard factor referred to in this context.
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